edX Proteins: Alignment, Analysis and Structure

University System of Maryland via edX

  • Overview
  1. edX
    Platform:
    edX
    Provider:
    University System of Maryland
    Effort:
    8 to 10 hours per week
    Length:
    8 weeks
    Language:
    English
    Credentials:
    Paid Certificate Available
    Part of:
    MicroMasters Program: Bioinformatics
    Overview
    Proteins play a very important role in all organisms. In fact, most of the work that happens inside every cell happens because a specific protein is employed for a specific task. Often the three-dimensional shape of a protein plays a major role in its function. As such, it is important to know the structure of all proteins to have an idea of what function they perform.

    One of the jobs of a bioinformatician is to predict the three-dimensional structure of a protein using only the DNA sequence that encodes it as well as determining the effects of any mutations in the DNA on the three-dimensional structure/function.

    In this course, part of the Bioinformatics MicroMasters program, you will learn about protein structure and its impact on function, practice aligning protein sequences to discover differences, and generate model structures of proteins using web and software-based approaches.

    What you'll learn
    • Analyze biological big data
    • How to align protein sequences to discover differences and determine structure
    • Generate model structures of unknown proteins
    Taught by
    Dr. James Coker

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