Dynamical Modeling Methods for Systems Biology

Coursera Dynamical Modeling Methods for Systems Biology

Platform
Coursera
Provider
Icahn School of Medicine at Mount Sinai
Effort
8 to 10 hours per week
Length
7 weeks
Language
English
Credentials
Paid Certificate Available
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Overview
An introduction to dynamical modeling techniques used in contemporary Systems Biology research.

We take a case-based approach to teach contemporary mathematical modeling
techniques. The course is appropriate for advanced undergraduates and beginning graduate students. Lectures provide biological background and describe the development of both classical mathematical models and more recent representations of biological processes. The course will be useful for students who plan to use experimental techniques as their approach in the laboratory and employ computational modeling as a tool to draw deeper understanding of experiments. The course should also be valuable as an introductory overview for students planning to conduct original research in modeling biological systems.

This course focuses on dynamical modeling techniques used in Systems Biology research. These techniques are based on biological mechanisms, and simulations with these models generate predictions that can subsequently be tested experimentally. These testable predictions frequently provide novel insight into biological processes. The approaches taught here can be grouped into the following categories: 1) ordinary differential equation-based models, 2) partial differential equation-based models, and 3) stochastic models.

Syllabus
  • Introduction | Computing with MATLAB
  • Introduction to Dynamical Systems
  • Bistability in Biochemical Signaling Models
  • Computational Modeling of the Cell Cycle
  • Modeling Electrical Signaling
  • Modeling with Partial Differential Equations
  • Stochastic Modeling

Taught by
Eric Sobie
Author
Coursera
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